US ZIP Code
45601

Chillicothe, OH

Ross County  ·  Ohio

● Active
👥 56,453 Population
💰 $57,430 Median HH Income
▼ 25% below avg ↑ 16% since 2019
🎂 41.1 Median Age
🏠 $160,800 Median Home Value
▼ 42% below avg ↑ 29% since 2019
🎓 27.9% College Grads
▼ 28% below avg
📊 4.9% Unemployment
≈ Avg ↓ 17% since 2019
ZIP Code Details
ZIP Code45601
CityChillicothe
StateOhio (OH)
CountyRoss County
Area Code220/740
Elevation693 ft
Latitude39.31206
Longitude-82.957071
TimezoneNew York (DST)
FIPS39141
ZIP TypeStandard
StatusActive
People & Population (ACS 2023)
♂ Male 53.0% (29,943) Female 47.0% (26,510) ♀

Race & Ethnicity

White: 86.1%Hispanic: 1.8%Black: 7.3%Asian: 0.5%Other: 4.1%Race
White86.1%
Hispanic1.8%
Black7.3%
Asian0.5%
Other4.1%

Age Breakdown

Under 5
5%
5–17
14%
18–24
8%
25–44
27%
45–64
28%
65+
9%

Key Indicators

Median Age41.1 yrs
Avg Household Size2.38
Below Poverty16.6% ▲ 66% above avg
College Grads27.9% ▼ 28% below avg
Unemployment4.9% ≈ Avg
No HS Diploma456 (1.2%)
HS Graduate16,142 (43.1%)
Some College5,464 (14.6%)
Associates4,933 (13.2%)
Bachelors3,224 (8.6%)
Graduate Degree7,200 (19.2%)

Education

No HS: 1.2%HS Grad: 43.1%Some College: 14.6%Associates: 13.2%Bachelors: 8.6%Graduate: 19.2%Edu
No HS1.2%
HS Grad43.1%
Some College14.6%
Associates13.2%
Bachelors8.6%
Graduate19.2%
Housing & Income

Housing Tenure

Owner: 69.4%Renter: 30.6%Tenure
Owner69.4%
Renter30.6%

Home Value Distribution

Under $50k
10%
$50k–100k
16%
$100k–150k
20%
$150k–200k
21%
$200k–300k
22%
$300k–500k
8%
Over $500k
3%

Financials

Median HH Income$57,430 ▼ 25% below avg ↑ 16% since 2019
Median Home Value$160,800 ▼ 42% below avg ↑ 29% since 2019
Home/Income Ratio2.8x (nat avg ~3.5x)
Median Rent$858/mo ↑ 14% since 2019
Total Units23,358
Vacant Units1,782
Avg HH Size2.38

Income Distribution

Under $25k
21%
$25k–50k
20%
$50k–75k
17%
$75k–100k
13%
$100k–150k
19%
$150k–200k
5%
Over $200k
5%
Employment & Commute

How People Get to Work

Drove Alone
92%
Public Transit
0%
Walked
2%
Work From Home
6%

Commute Time

Under 15 min
35%
15–30 min
37%
30–45 min
11%
Over 45 min
18%
Housing Stock

Year Built

Before 1940
3%
1940s–1950s
14%
1960s–1970s
11%
1980s–1990s
15%
2000+
56%

Summary

Total Units23,358
Vacant1,782
Owner Occupied69.4%
Renter Occupied30.6%
Avg HH Size2.38
Frequently Asked Questions
ZIP code 45601 is in Chillicothe, OH, in Ross County.
ZIP code 45601 is located in Ohio (OH).
ZIP code 45601 is in Ross County, OH.
ZIP 45601 observes the New York timezone. Daylight Saving Time is observed.
The estimated population of ZIP code 45601 is 56,453 people (ACS 2023).
The median household income in ZIP code 45601 is $57,430 (ACS 2023).
The median home value in ZIP 45601 is $160,800 (ACS 2023).
About ZIP Code 45601

ZIP code 45601 is located in Chillicothe, Ohio, within Ross County. With a population of 56,453, this is a highly populated ZIP code with a middle-aged community — the median age is 41.1 years. Economically, 45601 is a solidly middle-class ZIP code: the median household income of $57,430 is below the national average.

Real estate in ZIP code 45601 represents an affordable housing market. The median home value of $160,800 is below the national average. Renters can expect to pay around $858 per month in median rent. Homeownership is strong here — 69.4% of occupied units are owner-occupied, suggesting an established, stable residential community. Median home values have increased by 29% since 2019.

The population of 45601 is primarily White (86.08%). Residents are moderately educated — 27.9% hold a bachelor's degree or higher, which is below the national average. Poverty affects some residents at 16.6%. Household income has grown by 16% since 2019.

The unemployment rate in 45601 stands at 4.9%, which is near the national average. As in most parts of the country, driving alone is the dominant commute mode at 83%.

Overall, ZIP code 45601 in Chillicothe, OH is characterized as solidly middle-class, moderately educated, a middle-aged community, and predominantly owner-occupied. With 56,453 residents, a median household income of $57,430, and a median home value of $160,800, it offers a clear picture of life in this part of Ohio.